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retired hsd icr cd1 male breeders  (Inotiv)


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    Inotiv retired hsd icr cd1 male breeders
    Retired Hsd Icr Cd1 Male Breeders, supplied by Inotiv, used in various techniques. Bioz Stars score: 95/100, based on 214 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hsd+icr+cd+1/ICR+(CD-1)+outbred+mice/pm42323509-51-0-5
    Average 95 stars, based on 214 article reviews
    retired hsd icr cd1 male breeders - by Bioz Stars, 2026-10
    95/100 stars

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    Article Title: An acidic residue within the OCT4 dimerization interface of SOX17 is necessary and sufficient to overcome its pluripotency-inducing activity.
    Article Snippet: B6;CBA-Tg(Pou5f1-EGFP)2Mnn/J (OG2; Jackson Laboratory #004654 [Szabó et al., 2002]) mice and Hsd:ICR (CD-1) (ICR; Inotiv #030) mice were maintained at the Centre for ComparativeMedicine Research, The University of Hong Kong.

    Article Title: Meloxicam in the treatment of in vitro and in vivo models of urinary bladder cancer.
    Article Snippet: To assess the efficacy of meloxicam, a non-steroidal anti-inflammatory drug (NSAID), on three human urinary bladder-cancer cell lines (HT1376, T24 and 5637) and on mice urinary bladder cancer chemically induced by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN).. The in vitro effects of meloxicam were assessed by optical microscopy, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method, flow cytometry and comet assay.. In vivo, Hsd:ICR male mice were exposed to BBN in drinking water, over the course of 12 weeks.

    Article Title: Cellular Biophysics During Freezing of Rat and Mouse Sperm Predicts Post-thaw Motility
    Article Snippet: Caudal sperm of Hsd:ICR (CD-1) retired breeder mice (Harlan) were collected by excision from two mice.

    Article Title: An acidic residue within the OCT4 dimerization interface of SOX17 is necessary and sufficient to overcome its pluripotency-inducing activity
    Article Snippet: B6;CBA-Tg(Pou5f1-EGFP)2Mnn/J (OG2; Jackson Laboratory #004654 [ ]) mice and Hsd:ICR (CD-1) (ICR; Inotiv #030) mice were maintained at the Centre for Comparative Medicine Research, The University of Hong Kong.

    Article Title: Uncovering Hidden Phenotypes in NEX ‐Cre Mice: Behavioral and Cellular Alterations Demand Re‐Evaluation of a Widely Used Transgenic Line
    Article Snippet: Hsd: ICR (CD‐1) outbred mice, ex‐breeder , Inotiv (Envigo) , RRID:IMSR_CRL:022— Crl:CD1(ICR) mouse, outbred stock Cat. No . INOTIV:030.

    Article Title: An acidic residue within the OCT4 dimerization interface of SOX17 is necessary and sufficient to overcome its pluripotency-inducing activity
    Article Snippet: B6;CBA-Tg(Pou5f1-EGFP)2Mnn/J (OG2; Jackson Laboratory #004654 [Szabó et al., 2002]) mice and Hsd:ICR (CD-1) (ICR; Inotiv #030) mice were maintained at the Centre for ComparativeMedicine Research, The University of Hong Kong.

    Mouse Assay:

    Article Title: Trimeric polypeptide complexes comprising a collagen XVIII homotrimerization domain and/or a collagen xv homotrimerization and an agonist of a TNFR family costimulatory receptor, encoding polynucleotide thereof and method of use thereof to treat cancer
    Article Snippet: The cell lines were routinely screened for the absence of mycoplasma contamination by PCR using the Mycoplasma PlusTM Primer Set (Stratagene, Cedar Creek, TX, USA). .. Mice C57BL/6, BALB/c, Hsd:ICR (CD-1) and Hsd:athymic Nude-Foxn1 nu female mice were purchased from Harlan Iberica (Envigo, Barcelona, Spain). .. The cell lines were routinely screened for the absence of mycoplasma contamination by PCR using the Mycoplasma Plus Primer Set (Stratagene, Cedar Creek, TX, USA).

    Crocin Bleaching Assay:

    Article Title: Stereocilia fusion pathology in the cochlear outer hair cells at the nanoscale level
    Article Snippet: .. The following mouse strains were used in this study: C57BL/6JRccHsd (Inotiv, Horst, Netherlands; formerly Envigo: 043); CBA/CaOlaHsd (Inotiv: 209); Hsd:ICR (CD-1®) (Inotiv: 030). ..



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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    Inotiv hsd icr cd 1 mice
    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived from CD-1 mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).

    Journal: Scientific Reports

    Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo

    doi: 10.1038/s41598-025-34660-6

    Figure Lengend Snippet: Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived from CD-1 mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).

    Article Snippet: Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN).

    Techniques: Activation Assay, Derivative Assay, Incubation, Enzyme-linked Immunosorbent Assay, Western Blot

    The antibody response to protein antigens injected with aluminum adjuvants does not require functional NLRP3. ( A , B ) C57BL/6J WT and Nlrp3 -/- mice were injected twice with OVA and AH ( A ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( B ). The graphs show the mean ± SE of four mice per group. ( C , D ) CD-1 mice were treated with MCC950 or untreated and then injected twice with OVA and AH ( C ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( D ). The graphs show data from individual mice and the mean ± SE of 4–5 mice per group. ns – not significant (Student’s t-test, p > 0.05).

    Journal: Scientific Reports

    Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo

    doi: 10.1038/s41598-025-34660-6

    Figure Lengend Snippet: The antibody response to protein antigens injected with aluminum adjuvants does not require functional NLRP3. ( A , B ) C57BL/6J WT and Nlrp3 -/- mice were injected twice with OVA and AH ( A ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( B ). The graphs show the mean ± SE of four mice per group. ( C , D ) CD-1 mice were treated with MCC950 or untreated and then injected twice with OVA and AH ( C ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( D ). The graphs show data from individual mice and the mean ± SE of 4–5 mice per group. ns – not significant (Student’s t-test, p > 0.05).

    Article Snippet: Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN).

    Techniques: Injection, Functional Assay